The following peer-reviewed articles discuss multiple aspects of microbiology and pre-clinical experimentation related to the influence of potassium channels on hair growth. Each of the listed articles is relevant to the Research and Development of our products and/or is authored by a member of our Scientific Advisory Board. The articles are listed here to summarize the depth and breadth of scientific inquiry that stands behind Oxford Biolabs.
The articles are not intended to promote any specific ingredient, regimen, or use and should not be construed as evidence of the safety, effectiveness, or intended uses of the TRX2® product. The label should be consulted for intended uses and appropriate directions for use of the TRX2® product.
- Buhl, AE et al, Potassium Channel Conductance: A Mechanism Affecting Hair Growth both In Vitro and In Vivo. J Invest Dermatol, 98(3), 315-319.
- Camerino DC et al, Ion Channel Pharmacology J Am Soc Exp NeuroTherapeutics, 2007, 4, 184-198.
- Challinor-Rogers JL et al, Potassium channel openers and other regulators of KATP channels, Clin Exp Pharmacol Physiol. 1994, 21(8), 583-97.
- Czarnetzki B., Kerl H., Sterry W., 1992, Dermatologie und Venerologie. De Gruyter, pp 1-11.
- Davies GC et al, Novel and Established Potassium Channel Openers Stimulate Hair Growth In Vitro: Implications for their Modes of Action in Hair Follicles, J Invest Dermatol. 2005, 124(4), 686-94.
- Foitzik K et al, L-Carnitine–L-tartrate promotes human hair growth in vitro, Exp Dermatol, 2007, 16(11), 936-45.
- Jahangir A and Terzic A, KATP channel therapeutics at the bedside, J Mol Cell Cardiol, 2005, 39, 99-112.
- Knorr F, et al, Follicular transport route – research progress and future perspectives. Eur J Pharm Biopharm 2009, 71(2), 173-80.
- Lademann, J. and Patzelt, 2014, Follicular drug penetration. in “Topical Drug Bioavailability, Bioequivalence, and Penetration“ Vinod Shah, Howard I. Maibach, John Jenner (eds.), Springer, New York, pp 169-179.
- Li M et al, Minoxidil-Induced Hair Growth is Mediated by Adenosine in Cultured Dermal Papilla Cells: Possible Involvement of Sulfonylurea Receptor 2B as a Target of Minoxidil, J Invest Dermatol, 2001, 117(6), 1594-600.
- Meidan VM, Bonner MC, Michniak BB. Transfollicular drug delivery – is it a reality? Int J Pharm. 2005, 306(1-2), 1-14.
- Messenger AG et al, Minoxidil: mechanisms of action on hair growth, Br J Dermatol. 2004, 150(2), 186-94.
- Shorter K et al, Human hair follicles contain two forms of ATP- sensitive potassium channels, only one of which is sensitive to minoxidil, FASEB J, 2008, 22(6), 1725-1736.
- Steinmann E et al, Antiviral effects of amantadine and iminosugar derivatives against hepatitis C virus. Hepatology. 2007, 46(2), 330-338.
- Trüeb RM, Molecular mechanisms of androgenetic alopecia, Exp Gerontol, 2002, 37, 981-990.
- Vogt A, Mandt N, Lademann J, Schaefer H, Blume-Peytavi U. Follicular targeting – a promising tool in selective dermatotherapy. J Investig Dermatol Symp Proc. 2005, 10(3), 252-5
- Whitfield T et al, The influence of different lipid environments on the structure and function of the hepatitis C virus p7 ion channel protein, Mol Membr Biol, 2011, 28(5), 254-64. doi: 10.3109/09687688.2011.581253. Epub 2011 May 23.