Own Your Baldness in 5 Steps

Written by admin Apr 11th, 2014

You are in you 20′s, 30′s, 40′s and well… older but you still haven’t faced and accepted your condition, your hair is falling out and thinning. We know it’s not something everyone, especially men, look forward to nor is it an occasion to celebrate once it happens, but it doesn’t help if you just sulk around thinking about all the negative things you can think of about how bad it affects you, your lifestyle and your social life. Stop! Instead, focus your mind on the positive and what you can do about it. It will make you feel a whole lot better, less stressed, less worried and more happy, light and comfortable.

Look for signs

First, assess if what you are experiencing is really hair loss.

Have other people noticed your hair has thinned out?

Is more skin visible on your head than your hair?

Do you feel your hair is unusually thinner?

Accept it

I know there are 5 stages of acceptance: denial, anger, bargaining, depression and acceptance. Accepting that your hair has lived its life is hard, but learn how to accept it. You may have your own ways and even your own time but accept it… think of the positives. You still have hair on other parts of your body, you still have complete organs, supportive family and friends, etc.

Don’t cover it up

One of the many things that popped into your mind the moment you realized that you are going bald is to get a toupee/wig or maybe even wear hats 24/7. That won’t help. Consider the costs you will have to pay to buy it and maintain it. Do not cover it up.

Shave it off

One option is to shave whatever hair you have left on your head. Okay, that seems sudden but it might be a good thing to do and who knows, it might even give you a new and fresher edge. Shaved heads have already been embraced by the society – the only problem you’ll face during the first few days of your new do is your friends making jokes about how you look like a shiny crystal ball or the likes. But the good thing is the jokes will only last a few days while the good feeling you have will last longer.

Stay positive

This is a good thing to practice. The more positive you are, the less stressed you’ll become. Focus on the good things. Maintain proper upkeep once you have shaved your head – just because you don’t have hair doesn’t mean you don’t have to wash your head anymore. Treat your shaved head like your face – wash it with moisturizing soap, and make sure the product won’t clog your pores.

 

http://www.askmen.com/fashion/fashiontip_150/188b_fashion_advice.html

Derma rolling for hair loss

Written by admin Mar 28th, 2014

What is derma rolling

derma-roller1Derma rolling is a technique that involves rolling many tiny needles over the skin (called microneedling), making tiny pricks that may stimulate collagen production to smooth out the skin. Rejuvenating the skin is not an easy task and perhaps that is the reason why the there are not so many ways of doing it. One of the ways to do it is to cause mild injuries to the skin. What the body does in response is to repair immediately the injury by replacing the already injured skin with a new layer of skin. This is the main principle of derma rolling. The body is forced to renew the injured skin. However, manufacturers have revealed a new model that is being used to treat androgenic alopecia. How you ask? Read on.

Does it really work?

Derma rolling has become a popular process and many people have started embracing it. But the main question people ask is, “Does is it really work?” Some users have claimed that the does help with hair loss. However, this process needs a commitment to the treatment program. Growth of the hair relies on genes that develop the new hair cells. This happens within the hair follicles. These are the small openings covering the scalp and the rest of the body. There are different chemicals that need to be triggered so that they can produce hair cells. The human growth factor is one of the most important factors.

What scientists suggest is that the derma roller works by triggering production of the human growth factor. The needles that move on the skin cause minor wounds as in the case of skin treatment. The body works by producing new skin in the area of the injury by releasing growth hormones and many more chemicals that make the process faster. These chemicals are what supporters of derma rollers believe stimulate the growth of hair in the areas that have been affected by hair loss. This is what causes regrowth of hair.

What people are saying about derma rolling

As much as it might take long to see what derma rolling does to the hair, there has been a mix of reactions from patients about the treatment. Rodgers is one of the users who found the derma roller treatment helpful and efficient. He said that this treatment made his head feel better after the hair grew.  Another user said it was causing some shedding but that the existing hair was looking healthier than ever. Several users have complained about some discomfort while using the derma roller – from it being uncomfortable to even painful to use. Moreover, many people use a derma roller together with minoxidil, since microneedling helps allow the topical product penetrate deeper into the skin. The size of the microneedle can also determine how effective the treatment can be.

 

Future Treatment Options

Written by admin Mar 21st, 2014

The research and study for improved treatment options for hair loss is an ongoing science. Today’s available treatments such as hair supplements, surgery and topical solutions are also being developed for a much positive results for every hair loss sufferers who are all hoping for an effective product that will not just drain their pockets without giving them a good outcome from it. Most of the ongoing research that are being made are promising, however, for this to be available to the public it might still take years or even decades to come out with a perfected and safe product.

Don’t lose hope. Whether you are young or not-so-young or whether or not we live up to the day these future treatments are out, present treatments that are available are still as good and these future treatments will give us something to be hopeful about and look forward to the possibility of having a bald-free head.

Here are future treatment options that we can all look forward to and hope they continue and finish with their research.

Stem Cell Research

(Hair Cloning / Hair Multiplication)

Stem cell research has been around for years mostly in the pursuit for treatments for cancer, Alzheimer’s, Parkinson’s and injury of the spinal cord. This research is has received controversies about the embryonic cells. It is believed that these cells will induce specialized cells and tissues of the body. However, in hair loss we will not be dealing with this specific cells but with adult stem cells in the bulge area of the hair follicle. Adult stem cell has the ability to copy itself (self-renewal) and generate progenitor cells which will divide and become specialized cells of the hair shaft, inner root sheath, and outer root sheath.

These stem cells are removed from the person’s good hair follicle (most of the time at the back of the head) and will then be transplanted to the balding areas and will produce new hair follicles.

What scientists are trying to find out know is how chemical signals between the cells and the bulge area work. The adult stem cells and the bulge area remain irresponsive of each other until they get signals from epidermal cells and then they generate a intermediate state before they divide into specialized cells in the hair follicle or epidermal tissues.

This research is being done by several scientists and laboratories such as Aderans and Follica.

Sonic Hedgehog Gene

Hedgehog genes are present in flies to humans and there is a hedgehog signaling pathway which gives cells information they need to make embryo develop properly. This gene is can convert hair in resting phase to growing phase. Sonic Hedgehog is the most studied among the three Hedgehog homologues in mammals.

Hedgehog as a treatment is being developed by Curis Inc. and Procter and Gamble, a hedgehog agonist which is a drug for treatment of hair loss or hair growth disorders.

Gene Therapy

This is a more advanced treatment and is still in its infant stage. Since male pattern baldness is mostly from genetics, inn gene therapy you will change the genes and alter cell function.

From the American Hair Loss Association:

“Gene therapy requires learning how an inherited medical condition occurs at the DNA molecule level, and then going in and fixing it. With gene therapy, the hair follicles with DHT-sensitive cells could be changed into follicles with DHT-resistant cells, and the hair follicles would continue to grow new hairs for a lifetime. But gene therapy involves several very difficult to achieve steps. The first step is figuring out which of the tens of thousands of genes on strands of DNA are involved in the characteristic to be altered, and the second step is figuring out how exactly the target genes are to be changed, so that they give instructions for making the slightly different proteins that will achieve the desired effect. The third step is getting the target cells in the living organism to incorporate the new and improved genes as replacements for the old undesirable genes.”

Obviously, these future treatments really do seem too futuristic right now. They require extensive research and trials to make the treatment more effective than the products that we have right now. There’s nothing any of us can do but wait and see what these scientists and companies can develop. We can hope for the best that the research will be on our side. Still, there’s no doubt that results will not be available for another couple of years or so.

 

http://www.hairloss-reversible.com/

http://en.wikipedia.org/wiki/Hedgehog_signaling_pathway

http://www.americanhairloss.org/hair_loss_research/introduction.asp

The Latest Medical Treatments against Male and Female Pattern Baldness

Written by admin Feb 19th, 2014

There being so many questions whether science is doing something for people who experience hair loss both male and female, it is important to note that different contenders have done their research to come up with different therapies to cure people with Androgenetic Alopecia.

Histogen, Follica, Trichoscience, Aderans and Oxford BioLabs are the main companies on the fight against Androgenetic Alopecia. We will analyze each company and what they have been able to achieve so far.

Histogen has finally published their 12 month Phase I/II results. They have been able to evaluate a bioengineered human cell-derived formulation known as the Hair Stimulating Complex (HSC). Thanks to their 2013 research, they have been able to maintain the quiescent state of hair follicle stem cell proliferation with cells grown on beads in hypoxic bioreactors. They have hypothised the injection of this medium leading to an increase in the thickness of the hairs and a reversal of the miniaturization process. We hope this turns out well and HSC will simply be used in your most problematic areas to give you that extra boost in hair density.

Follica, a U.S.-based firm, says they are very close to unleashing the product that will finally draw the curtains on the dreaded hair loss. According to their 2013 science report, they claim their proprietary procedure consistently creates new hair follicles in both men and women. In his press release, Dr. William Ju said that Follica has now developed a technology platform suited to support clinical translation of the new findings. After all these years, they have finally promised to prop up the male ego.

TrichoScience is now owned by RepliCel, a regenerative medicine company focused on developing cell therapies that treat functional cellular deficits including chronic tendinosis, pattern baldness and skin aging. The company has planned for the 2014 initiation of Phase 2 trials on the RCT-01 treatment for Achilles tendinosis and RCH-01 treatment for pattern baldness. The company is also developing a unique programmable cell injector device for dermal injection and they hope this will stand out. They are also expected to release their product in 2014.

Aderans is attempting to come up with a real hair cloning technology. The Ji Game process has been tested and has been seen to remove hair follicle cells from a patient’s neck and multiply new cells. The company is now in its Phase II clinical trials across North America.

Oxford BioLabs’s treatment tackles hair loss by stimulating potassium ion channels within hair follicles. The company’s flagship product, TRX2™ Molecular Supplement Capsules, has established itself as a viable alternative to pharmaceuticals and has become one of Europe’s best-selling hair loss supplements. Oxford BioLabs is currently working towards expanding the TRX2 platform technology to other products.

So far those are the latest updates in the clinical process, but we will always update you on what’s happening through our posts and articles on hair loss treatments.

Hair loss product ‘neogenic’ by L’Oreal

Written by Dr. Tristan Barmer Jul 8th, 2012

The well- known cosmetic company L’oreal announced that in September 2012 they will be launching a new hair loss product that, according to them, will help awakening dormant hair follicles and enhance hair density. The news about this upcoming hair loss product has recenlty been disclosed by CosmeticsDesign-Europe.com.

L’Oreal’s upcoming hair loss product “Neogenetic” – a snake oil?

The new hair loss product will be in lotion form and will be named ‘Neogenic’, which is named after the phase of turning from hair follciles from dormancy into activity.

Retail price for the 1 month hair loss treatment will be around €90 (a 24-pack). The company said that they are planning to produce other forms of Neogenic in the future such as hair loss shampoos, lotions and mousses.  Read More »

Trx2 ACell Interview with Hair Transplant Expert Dr. Gary Hitzig *Exclusive, Part 3

Written by admin Jul 5th, 2012

Please note: This is a reprint of the interview that has taken place in March 2010 between Dr. Hitzig and TRX2.

This is the third instalment and photos of our EXCLUSIVE interview with hair transplant expert Dr. Gary Hitzig regarding the ability of ACell’s ECM technology to be used during hair transplant procedures. Part 1 can be found here and part 2 here.

Attention: Some photos contain blood and wound bleeding. Don’t watch this if you are sensible to such views. 

Step 1: Scar was excised – prior to Acell insertion.

 

 

 

 

 

 

 

 

 

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Trx2 ACell Interview with Hair Transplant Expert Dr. Gary Hitzig *Exclusive, Part 2*

Written by Dr. Thomas Whitfield DPhil Jun 29th, 2012

Please note: This is a reprint of the interview that has taken place in March 2010 between Dr. Hitzig and TRX2.

This is the second installment of our EXCLUSIVE interview with hair transplant expert Dr. Gary Hitzig regarding the ability of ACell’s ECM technology to be implemented during hair transplant procedures. Part 1 can be found here.

ACell and platelet rich plasma (PRP) injected into the scalp prior to a hair transplant surgery.

 

 

 

 

 

 

 

 

 

 

 

TRX2: In 2007, a dermatology professor at the University of Pennsylvania named George Cotsarelis published a paper providing strong evidence that wound healing can contribute to follicular neogenesis if certain conditions are met. Are you familiar with this particular research? Do you think it is possible to simply wound the skin (via dermabrasion) and apply the ACell powder in order to elicit hair growth? In other words, how big of a wound is necessary on the scalp to regenerate follicles in the skin?

Dr. Hitzig: To be honest, I have an enormous stack of research that I’ve been reading through. I’m positive that paper is in there somewhere. We are definitely operating with the same mechanisms. The processes we are observing rely on producing an embryonic environment for regeneration.

In regards to your second question, that was one of the first things we tried. Here’s why it doesn’t work with ACell (unfortunately). The process of regeneration can be likened to a copy machine. In this case, what are you really copying? Defective cells? Dead hair? You need to give ACell something healthy to mimic and copy.  Otherwise it will only regenerate bald skin. We are hoping to get different results with our injections during hair transplant procedures.

TRX2: A hair is a mini-organ. It makes sense that given ACell’s inability to completely reconstruct other organs like hearts, it shouldn’t be able to reconstruct a hair follicle. How do you respond to this idea?

Dr. Hitzig: Well, let’s be honest, ACell certainly has its limitations. You can’t make a heart per se, but you can certainly rebuild the muscles and nerves that a heart consists of. You need to focus on the repair. It can be modeled and then targeted for specific areas. For instance, ACell has already been used to regenerate esophagi, bladders and even ears. It’s naïve to immediately discount the technology just because it can’t regenerate a fully-functioning heart. This process is difficult and it is complicated, but it can be enhanced to obtain the desired results. The body has the innate ability to regenerate itself; it just needs a considerable amount of assistance.

Once again, the basement membrane not only regenerates the skin with great quality, it also brings in the blood supply, cells and nerves too. This not just a veneer, ACell provides all of the necessary internal structures.  Read More »

Trx2 ACell Interview with Hair Transplant Expert Dr. Gary Hitzig *Exclusive, Part 1*

Written by Dr. Thomas Whitfield DPhil Jun 26th, 2012

Dr. Hitzig ACell hair transplant expert exclusive interview Part 1 (Part 2 to follow):

Please note: This is a reprint of the exclusive interview that has taken place in March 2010 between Dr. Hitzig and TRX2.

Dr. Hitzig (R) observes ACell Platelet Rich Plasma (PRP) injections during a hair transplant surgery while working with scientists in London, UK.

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Because of its unique ability to heal a variety of full-thickness wounds with no visible scarring, many people in the hair transplant community have been inquiring about the use of ACell MatriStem products during hair restoration procedures.

This recent press release from hair transplant experts Dr. Jerry Cooley and Dr. Gary Hitzig indicated that the Extracellular Matrix products developed by ACell, Inc. might indeed be very effective for this purpose. In order to address the growing skepticism/excitement regarding ACell’s ability to heal hair transplant donor scars and regenerate donor hair, hair transplant expert Dr. Gary Hitzig was kind enough to grant TRX2 with an exclusive interview to explain the procedure.

How long have you been experimenting with ACell’s MatriStem products?

Since September 2008, when the FDA approved it for use.

How many patients have you treated?

The initial cohort I treated was between 18 and 20 people. I am currently writing a scientific article based on the results from this group; explaining the rationale behind the unique regenerative process we’ve observed. Once all of the documentation has been organized and all of the patient follow-ups have been completed, the research will be sent to ACell for verification of claims. Publication should follow shortly thereafter.

More recently, however, I’ve been able to treat a slightly larger group of hair transplant patients with a much wider array of applications. This is the most exciting aspect of my research.

Read More »

Current Hair Loss Treatments: What You Can Do to Take Control of Your Hair Loss Today

Written by Dr. Tristan Barmer May 24th, 2012

There is still no “cure” for Androgenetic Alopecia. Although there are many promising hair loss treatments currently in development, it is unlikely that any of these hair loss therapies will be able to reach the market before a considerable amount of safety trials have been conducted in a controlled and clinical setting. This process takes time. Fortunately, there are several hair loss treatment options that are available to temporarily halt hair loss – many of which simultaneously revive, strengthen and nourish existing hair follicles.

We have outlined several of these existing hair loss therapies, all of which you can use today to take control of your hair loss until superior hair loss treatment options become available. Read More »

Medical Conditions That Cause Excessively Dry Hair

Written by Dr. Tristan Barmer Feb 3rd, 2012

Hair is often considered an accessory, which is styled to fit a mood, suit the occasion or to make a statement. But when hair becomes unmanageable, several hair care products serve as quick remedies that seem effective. Though the results may be lasting and effective, the damage these ingredients cause may result in long-term effects. With so much hype and media advertisements on these hair care products, women especially believe hair gels, mousse, hair spray are the saviors for a hair that looks limp and dry. Dryness, dullness, brittleness, hair fall, split ends and dandruff are some effects of these harsh products. Pollution, smoke, dry weather, chlorine and UV rays are other contributing factors to excessively dry hair. These are the non-medical contributors for dry hair.

The following are known medical conditions that can cause excessively dry and brittle hair: Read More »